Papers

Welte Papers Directory

Haste makes waste
Klar ensures thermal robustness of oskar localization by restraining RNP motility. I. Gaspar, Y. V. Yu, S. L. Cotton, D.-H. Kim, A. Ephrussi, M. A. Welte (2014). J. Cell Biol. 206: 199-215
Lipid droplets act as short-term histone buffers
Drosophila lipid droplets buffer the H2Av supply to protect early embryonic development. Z. Li, M. Johnson, Z. Ke, L. Chen, M. A. Welte (2014). Curr. Biol. 24: 1485-1491
Selecting embryos of the correct genotype using droplet transport mutants
A conserved role for Snail as a potentiator of active transcription. M. Rembold, L. Ciglar, J. O. Yáñez-Cuna, R. P. Zinzen, C. Girardot, A. Jain, M. A. Welte, A. Stark, M. Leptin, E. E. M. Furlong (2014). Genes Dev. 28: 167-181
Klar is really complicated
Novel isoforms of the transport regulator Klar. D.-H. Kim, S. L. Cotton, D. Manna, M. A. Welte (2013). PLoS ONE 8: e55070
Keeping the bugs out: lipid-droplet bound histones in innate immunity
A novel role for lipid droplets in the organismal antibacterial response.P. Anand, S. Cermelli, Z. Li, A. Kassan, M. Bosch, R. Sigua, L. Huang, A. J. Ouellette, A. Pol, M. A. Welte, S. P. Gross (2012). eLife 1: e00003
Lipid droplets ARE protein sequestration sites
Lipid droplets control the maternal histone supply of Drosophila embryos. Z. Li, K. Thiel, P. J. Thul, M. Beller, R. Kühnlein, M. A. Welte. (2012). Curr. Biol. 22: 2104-2113
Klar controls nuclear positioning in muscles
Organelle positioning in muscles: Cooperation between two distinct KASH proteins and microtubules. H. Elhanany-Tamir, Y. V. Yu, M. Shnayder, Ankit Jain, M. Welte, T. Volk (2012). JCB 198: 833-846
Identity of a lipid-droplet protein
Targeting the motor regulator Klar to lipid droplets Y. V. Yu, Z. Li, N. P. Rizzo, J. Einstein, M. A. Welte (2011). BMC Cell Biology 12: 9
Fast evolution of a core component of the RNAi machinery
Natural variation of the amino-terminal glutamine-rich domain of Drosophila Argonaute2 is not associated with developmental defects D. Hain, B. Bettencourt, K. Okamura, T. Csorba, W. Meyer, Z. Jin, J. Biggerstaff, H. Siomi, G. Hutvagner, E. Lai, M. A. Welte, H.-A.J. Müller (2010). PLoS ONE 5, e15264
Take your embryos for a spin
In-vivo Centrifugation of Drosophila Embryos. Susan L. Tran, Michael A. Welte. JoVE. 40. http://www.jove.com/index/details.stp?id=2005, doi: 10.3791/2005 (2010).
Motor balance by force?
Bidirectional transport: Matchmaking for motors. M. A. Welte. Curr. Biol. 20: R410-R413 (2010).
Lipid-droplet motion - a primer
Fat on the move: Intracellular motion of lipid droplets. M. A. Welte. Biochem. Soc. Trans. 37:991-996 (2009).
Getting Fat down PAT
"PAT proteins, an ancient family of lipid droplet proteins that regulate cellular lipid stores". Perry E. Bickel, John T. Tansey, Michael A. Welte. Biochimica et Biophysica Acta 1791:419-440 (2009).
Counting Motors
"Consequences of motor copy number on the intracellular transport of kinesin-1–driven lipid droplets". G. T. Shubeita, S. L. Tran, J. Xu, M. Vershinin, S. Cermelli, S.L. Cotton, M. A. Welte, S. P. Gross. Cell 135:1098-1107 (2008). Abstract
This article was highlighted in a Preview in the same issue of Cell.
Tug-of-war or coordinated motion: Maybe both ideas are true
"Molecular Motors: a traffic cop within?" M. A. Welte and S. P. Gross. HFSP J 2:178-182 (2008). Abstract
Lipid droplets: beyond fat
"Proteins under new management: lipid droplets deliver". Welte, M.A. TCB 17:363-369 (2007).
Lipid droplets are protein storage depots
"The lipid-droplet proteome reveals that droplets are a protein storage depot". S. Cermelli, Y. Guo, S. P. Gross, M. A. Welte. Curr. Biol. 16:1783-1795 (2006). Abstract
This paper was highlighted in a Dispatch article in Current Biology.
Role of Argonaute proteins in embryonic development
"Overlapping functions of Argonaute proteins in patterning and morphogenesis of Drosophila embryos". W. Meyer, S. Schreiber, Y. Guo, T. Volkmann, M. A. Welte, H.-A.J. Muller. PLoS Genetics 2: 1224-1239 (2006). Abstract
LSD2: A conductor for droplet transport
"Regulation of lipid-droplet transport by the Perilipin homologue LSD2". M. A. Welte, S. Cermelli, J. Griner, A. Viera, Y. Guo, D.-H. Kim, J. G. Gindhart, S. P. Gross. Curr. Biol. 15:1266-1275 (2005). Abstract
This paper was highlighted in a Dispatch article in Current Biology.
Isoform variation of the coordinator Klar
"Organelle-specific control of intracellular transport: Distinctly targeted isoforms of the regulator Klar ". Y. Guo, S. Jangi, M. A. Welte. Mol. Biol. Cell 16:1406-1416 (2005). Abstract
Bidirectional transport - a review
"Bidirectional transport along microtubules ". M. A. Welte. Curr. Biol. 14:R525-R537 (2004). Abstract
Determining Direction
"A Determinant for Directionality of Organelle Transport in Drosophila Embryos". SP Gross, Y Guo, JE Martinez, MA Welte. Curr. Biol. 13:1660-1668 (2003). Abstract
This paper was highlighted in a Dispatch article in Current Biology.
Are opposite-polarity motors coordinated?
"Coordination of opposite-polarity microtubule motors". S P Gross, MA Welte, S M Block, E F Wieschaus. J Cell Biol. 156:715-724 (2002). Abstract
Control of Cytoplasmic Dynein
"Dynein-mediated cargo transport in vivo. A switch controls travel distance". SP Gross, MA Welte, SM Block, EF Wieschaus. J Cell Biol. 148:945-956 (2000). Abstract
Klar Functions in Nuclear Migration and Lipid Droplet Transport in early Drosophila embryos
"Developmental regulation of vesicle transport in Drosophila embryos: forces and kinetics". MA Welte, SP Gross, M Postner, SM Block, EF Wieschaus. Cell 92:547-557 (1998). Abstract
This paper was highlighted in a Dispatch article in Current Biology.
Identifying the crucial lesion in a heat-induced developmental defect
"The basis for a heat-induced developmental defect: defining crucial lesions". MA Welte, I Duncan, S Lindquist. Genes Dev. 9:2240-2250 (1995).
Heat-Shock Protein 70 (Hsp70) protects against heat stress
"A new method for manipulating transgenes: Engineering heat tolerance in a complex multicellular organism". MA Welte, JM Tetrault, RP Dellavalle, S Lindquist. Curr Biol 3:842-853 (1993). Abstract
Hsp70 in Stress Tolerance
"Heat-Shock Proteins in Stress Tolerance". S Lindquist, DA Parsell, Y Sanchez, J Taulien, EA Craig, MA Welte. UOEH 15:1-10 (Suppl.) (1993).