2024
- Morandini F, Seluanov A, Gorbunova V. Slow and steady lives the longest. Nature Aging, 2024
- Paine PT, Rechsteiner C, Morandini F, …, Seluanov A, Gorbunova V, Ocampo A. Initiation phase cellular reprogramming ameliorates DNA damage in the ERCC1 mouse model of premature aging. Frontiers in Aging, 2024.
2023
- Brosh RB, Moskalev A, Gorbunova V. DNA repair and interventions in aging. Frontiers in Aging, 2023.
- Zhao Y, Zheng Z, Zhang Z, Xu Y, Hillpot E, Lin YS, Zakusilo FT, Lu JY, Ablaeva J, Biashad SA, Miller RA, Nevo E, Seluanov A, Gorbunova V. Evolution of high-molecular-mass hyaluronic acid is associated with subterranean lifestyle. Nature Communications, 2023.
- Romanenko SA, …, Seluanov A, Gorbunova V, Azpurua J, Pereira JC, Ferguson-Smith MA, Graphodatsky AS. Integration of fluorescence in situ hybridization and chromosome-length genome assemblies revealed synteny map for guinea pig, naked mole-rat, and human. Scientific Reports, 2023.
- Brochard T, McIntyre RL, Houtkooper RH, Seluanov A, Gorbunova V, Janssens GE. Repurposing nucleoside reverse transcriptase inhibitors (NRTIs) to slow aging. Ageing Research Reviews, 2023.
- Takasugi M, Ohtani N, Takemura K, Emmrich S, Zakusilo FT, …, Seluanov A, Gorbunova V. CD44 correlates with longevity and enhances basal ATF6 activity and ER stress resistance. Cell Reports, 2023.
- Zhang Z, Tian X, Lu JY, Boit K, Ablaeva J, Zakusilo FT, Emmrich S, Firsanov D, Rydkina E, Biashad SA, Lu Q, Tyshkovskiy A, Gladyshev VN, Horvath S, Seluanov A, Gorbunova V. Increased hyaluronan by naked mole-rat Has2 improves healthspan in mice. Nature, 2023.
- Haghani A, …, Ablaeva J, …, Emmrich S, …, Macoretta N, …, Rydkina E, …, Takasugi M, …, Zhang Z, Zhao Y, …, Seluanov A, Gorbunova V, …, Horvath S. DNA methylation networks underlying mammalian traits. Science, 2023
- Lu AT, …, Ablaeva J, …, Emmrich S, …, Gorbunova V, …, Macoretta N, …, Rydkina E, …, Seluanov A, …, Takasugi M, …, Zhang Z, …, Zhao Y, …, Horvath S. Universal DNA methylation age across mammalian tissues. Nature Aging, 2023.
- Tyshkovskiy A, …, Seluanov A, Schork NJ, Gorbunova V, Dmitriev SE, Miller RA, Gladyshev VN. Distinct longevity mechanisms across and within species and their association with aging. Cell, 2023.
- Vijg J, …, Gorbunova V, …, Walsh K. Mitigating age-related somatic mutation burden. Trends in Molecular Medicine, 2023
- Frohlich J, …, Gorbunova V, Vinciguerra M. Human centenarian–associated SIRT6 mutants modulate hepatocyte metabolism and collagen deposition in multilineage hepatic 3D spheroids. Geroscience, 2023.
- Athar F, Seluanov A, Gorbunova V. Bat crazy iPSCs. Cell, 2023.
- Zhao Y, Simon M, Seluanov A, Gorbunova V. DNA damage and repair in age-related inflammation. Nature Reviews Immunology, 2023.
- Gorbunova V, Seluanov A. Introduction: Progression of the Science of Ageing. Biochemistry and Cell Biology of Ageing: Part III Biomedical Science, 2023.
2022
- Simon M, Yang J, Gigas J, Earley EJ, Hillpot E, Zhang L, Zagorulya M, Tombline G, Gilbert M, Yuen SL, Pope A, Van Meter M, Emmrich S, Firsanov D, Athreya A, Biashad SA, …, Seluanov A, Suh Y, Gorbunova V. A rare human centenarian variant of SIRT6 enhances genome stability and interaction with Lamin A. The EMBO Journal, 2022.
- Fatima I, …, Seluanov A, Smith ESJ, Gorbunova V, …, Botchkarev VA. Skin aging in long-lived naked mole-rats is accompanied by increased expression of longevity-associated and tumor suppressor genes. Journal of Investigative Dermatology, 2022
- Emmrich S, Trapp A, Tolibzoba Zakusilo F, …, Zhang Z, Drage MG, Takasugi M, …, Seluanov A, Gorbunova V. Characterization of naked mole‐rat hematopoiesis reveals unique stem and progenitor cell patterns and neotenic traits. The EMBO Journal, 2022.
- Lu JY, Simon M, Zhao Y, Ablaeva J, Corson N, …, Seluanov A, Gorbunova V. Comparative transcriptomics reveals circadian and pluripotency networks as two pillars of longevity regulation. Cell Metabolism, 2022.
- Bettinger JQ, Simon M, Korotkov A, …, Seluanov A, Gorbunova V, Ghaemmaghami S. Accurate proteomewide measurement of methionine oxidation in aging mouse brains. Journal of Proteome Research, 2022.
- Taylor JR, …, Gorbunova V, Seluanov A, …, Helfand SL. Sirt6 regulates lifespan in Drosophila melanogaster. Proceedings of the National Academy of Sciences, 2022.
- Buffenstein R, …, Azpurua J, …, Gorbunova V, Hine C, …, Seluanov A, …, Tian X, …, Smith ESJ. The naked truth: a comprehensive clarification and classification of current ‘myths’ in naked mole‐rat biology. Biological Reviews, 2022.
- Kerepesi C, Meer MV, Ablaeva J, …, Seluanov A, …, Gorbunova V, Gladyshev VN. Epigenetic aging of the demographically non-aging naked mole-rat. Nature Communications, 2022.
- Makarova N, Kalaparthi V, Seluanov A, Gorbunova V, Dokukin ME, Sokolov I. Correlation of cell mechanics with the resistance to malignant transformation in naked mole rat fibroblasts. Nanoscale, 2022.
- Horvath S, Haghani A, Macoretta N, Ablaeva J, …, Takasugi M, Zhao Y, Rydkina E, Zhang Z, Emmrich S, Raj K, Seluanov A, Faulkes CG, Gorbunova V. DNA methylation clocks tick in naked mole rats but queens age more slowly than nonbreeders. Nature Aging, 2022.
2021
- Chesnokova V, …, Gorbunova V, Karalis K, Melmed S. Local non-pituitary growth hormone is induced with aging and facilitates epithelial damage. Cell Reports, 2021.
- Zakusilo FT, …, Seluanov A, Gorbunova V. Matters of size: Roles of hyaluronan in CNS aging and disease. Ageing Research Reviews, 2021.
- Korotkov A, Seluanov A, Gorbunova V. Sirtuin 6: linking longevity with genome and epigenome stability. Trends in Cell Biology, 2021.
- Zhao Y, Seluanov A, Gorbunova V. Revelations About Aging and Disease from Unconventional Vertebrate Model Organisms. Annual Review of Genetics, 2021.
- Lu JY, Seluanov A, Gorbunova V. Long-lived fish in a big pond. Science, 2021.
- Zhang Q, Tombline G, Ablaeva J, …, Zhao Y, …, Seluanov A, Gladyshev VN, Gorbunova V, Zhang ZD. Genomic expansion of Aldh1a1 protects beavers against high metabolic aldehydes from lipid oxidation. Cell Reports, 2021
- Zhang L, Dong X, Tian X, Lee M, Ablaeva J, Firsanov D, …, Seluanov A, Gorbunova V, Vijg J. Maintenance of genome sequence integrity in long-and short-lived rodent species. Science Advances, 2021
- Zhao Y, …, Zheng Z, Lu JY, Lee J, Ke Z, Ablaeva J, …, Seluanov A, Gorbunova V. Transposon-triggered innate immune response confers cancer resistance to the blind mole rat. Nature Immunology, 2021.
- Emmrich S, Zakusilo FT, Trapp A, …, Seluanov A, Gorbunova V. Ectopic cervical thymi and no thymic involution until midlife in naked mole rats. Aging Cell, 2021.
- Lin J, …, Gorbunova V, …, Zhang ZD. Rare genetic coding variants associated with human longevity and protection against age-related diseases. Nature Aging, 2021.
- Gorbunova V, Seluanov A, …, Sedivy JM. The role of retrotransposable elements in ageing and age-associated diseases. Nature, 2021.
- Morevati M, …, Gorbunova V, Olgaard K, Lewin E. Extrarenal expression of α-klotho, the kidney related longevity gene, in Heterocephalus glaber, the long living Naked Mole Rat. Scientific Reports, 2021.
- Kacprzyk J, …, Gorbunova V, …, Teeling EC. Evolution of mammalian longevity: age-related increase in autophagy in bats compared to other mammals. Aging (Albany NY), 2021.
- Augereau A, …, Gorbunova V, Gilson E, Gladyshev VN. Naked mole rat TRF1 safeguards glycolytic capacity and telomere replication under low oxygen. Science Advances, 2021.
- Swovick K, Firsanov D, …, Seluanov A, Gorbunova V, Ghaemmaghami S. Interspecies Differences in Proteome Turnover Kinetics Are Correlated With Life Spans and Energetic Demands. Molecular & Cellular Proteomics, 2021.
2020
- Mkrtchyan GV, …, Gorbunova V, …, Scheibye-Knudsen M. ARDD 2020: from aging mechanisms to interventions. Aging (Albany NY), 2020.
- Pawelec G, …, Gorbunova V, …, Seluanov A, …, Cohen AA. The conundrum of human immune system “senescence”. Mechanisms of Ageing and Development, 2020
- Taguchi T, Kotelsky A, Takasugi M, Chang M, Ke Z, Betancourt M, …, Seluanov A, Gorbunova V. Naked mole-rats are extremely resistant to post-traumatic osteoarthritis. Aging Cell, 2020.
- Cohen AA, …, Gorbunova V, …, Fülöp T. Lack of consensus on an aging biology paradigm? A global survey reveals an agreement to disagree, and the need for an interdisciplinary framework. Mechanisms of Ageing and Development, 2020.
- Simon M, Emmrich S, Seluanov A, Gorbunova V. A hairy tale: SIRT7 safeguards skin stem cells during aging. The EMBO Journal, 2020.
- Gorbunova V, Takasugi M, Seluanov A. Hyaluronan goes to great length. Cell Stress, 2020
- Ke Z, Firsanov D, Spencer B, Seluanov A, Gorbunova V. Short-term calorie restriction enhances DNA repair by non-homologous end joining in mice. NPJ Aging and Mechanisms of Disease, 2020.
- Zhang ZD, …, Gorbunova V, …, Vijg J. Genetics of extreme human longevity to guide drug discovery for healthy ageing. Nature Metabolism, 2020
- Zhou X, …, Tian X, …, Seluanov A, Zhang ZD, Gorbunova V, Liu X, Gladyshev VN. Beaver and naked mole rat genomes reveal common paths to longevity. Cell Reports, 2020
- Gorbunova V, Seluanov A, Kennedy BK. The World Goes Bats: Living Longer and Tolerating Viruses. Cell Metabolism, 2020.
- Rezazadeh S, Yang D, Biashad SA, Firsanov D, Takasugi M, Gilbert M, Tombline G, Bhanu NV, Garcia BA, Seluanov A, Gorbunova V. SIRT6 mono-ADP ribosylates KDM2A to locally increase H3K36me2 at DNA damage sites to inhibit transcription and promote repair. Aging (Albany NY), 2020
- Kumar V, …, Gorbunova V, Seluanov A, …, Nawroth PP. Compromised DNA repair is responsible for diabetes-associated fibrosis. The EMBO Journal, 2020.
- Takasugi M, Firsanov D, Tombline G, Ning H, Ablaeva J, Seluanov A, Gorbunova V. Naked mole-rat very-high-molecular-mass hyaluronan exhibits superior cytoprotective properties. Nature Communications, 2020.
- Tombline G, Gigas J, Macoretta N, Zacher M, Emmrich S, Zhao Y, Seluanov A, Gorbunova V. Proteomics of Long-Lived Mammals. Proteomics, 2020.
- Zhao J, Tian X, Zhu Y, Zhang Z, Rydkina E, …, Cornwell A, …, Seluanov A, Fang X, Gorbunova V. Reply to: Transformation of naked mole-rat cells. Nature, 2020.
2019
- Chen Y, Zhang H, Xu Z, …, Tian X, Seluanov A, …, Gorbunova V, Mao Z. A PARP1-BRG1-SIRT1 axis promotes HR repair by reducing nucleosome density at DNA damage sites. Nucleic Acids Research, 2019.
- Katagi H, …, Tian X, Seluanov A, Gorbunova V, …, Hashizume R. Radiosensitization by Histone H3 Demethylase Inhibition in Diffuse Intrinsic Pontine Glioma. Clinical Cancer Research, 2019.
- Rezazadeh S, Yang D, Tombline G, Simon M, Regan SP, Seluanov A, Gorbunova V. SIRT6 promotes transcription of a subset of NRF2 targets by mono-ADP-ribosylating BAF170. Nucleic Acids Research, 2019.
- Tian X, Firsanov D, Zhang Z, Cheng Y, Luo L, Tombline G, Tan R, Simon M, Henderson S, Steffan J, Goldfarb A, Tam J, Zheng K, Cornwell A, Johnson A, …, Seluanov A, Gorbunova V. SIRT6 Is Responsible for More Efficient DNA Double-Strand Break Repair in Long-Lived Species. Cell, 2019.
- Simon M, Van Meter M, Ablaeva J, Ke Z, Gonzalez RS, Taguchi T, …, Seluanov A, Gorbunova V. LINE1 Derepression in Aged Wild-Type and SIRT6-Deficient Mice Drives Inflammation. Cell Metabolism, 2019.
- Núñez FJ, …, Gorbunova V, …, Castro MG. IDH1-R132H acts as a tumor suppressor in glioma via epigenetic up-regulation of the DNA damage response. Science Translational Medicine, 2019.
- De Cecco M, …, Simon M, Seluanov A, Gorbunova V, …, Sedivy JM. L1 drives IFN in senescent cells and promotes age-associated inflammation. Nature, 2019.
- Chesnokova V, …, Gorbunova V, Melmed S. Excess growth hormone suppresses DNA damage repair in epithelial cells. JCI Insight, 2019
2018
- Bourque G, …, Gorbunova V, Seluanov A, …, Feschotte C. Ten things you should know about transposable elements. Genome Biology, 2018.
- Seluanov A, Gladyshev VN, Vijg J, Gorbunova V. Mechanisms of cancer resistance in long lived mammals. Nature Reviews Cancer, 2018.
- Evdokimov A, …, Seluanov A, Gorbunova V, …, Lavrik O. Naked mole rat cells display more efficient excision repair than mouse cells. Aging (Albany NY), 2018.
- Swovick K, Welle KA, Hryhorenko J, Seluanov A, Gorbunova V, Ghaemmaghami S. Cross-species comparison of proteome turnover kinetics. Molecular & Cellular Proteomics, 2018.
- Tian X, Doerig K, Park R, Can Ran Qin A, Hwang C, Neary A, Gilbert M, Seluanov A, Gorbunova V. Evolution of telomere maintenance and tumour suppressor mechanisms across mammals. Philosophical Transactions of the Royal Society B: Biological Sciences, 2018
- Ke Z, Seluanov A, Gorbunova V. Accurate translation is important for fidelity. Aging (Albany NY), 2018.
- Ghosh S, …, Gorbunova V, Liu X, Zhou Z. Haploinsufficiency of Trp53 dramatically extends the lifespan of Sirt6-deficient mice. eLife, 2018.
- Zhao Y, …, Tian X, …, Seluanov A, Gorbunova V. Naked mole rats can undergo developmental, oncogene-induced and DNA damage-induced cellular senescence. Proceedings of the National Academy of Sciences, 2018.
- D Piscitello, …, V Gorbunova, A Seluanov, DA Gillespie, PD Adams. AKT overactivation can suppress DNA repair via p70S6 kinase-dependent downregulation of MRE11. Oncogene, 2018.
2017
- Tan L, Ke Z, Tombline G, Macoretta N, Hayes K, Tian X, Lv R, Ablaeva J, Gilbert M, …, Seluanov A, Gorbunova V. Naked Mole Rat Cells Have a Stable Epigenome that Resists iPSC Reprogramming. Stem Cell Reports, 2017.
- Tian X, Seluanov A, Gorbunova V. Molecular Mechanisms Determining Lifespan in Short- and Long-Lived Species. Trends in Endocrinology & Metabolism, 2017.
- Ke Z, …, Seluanov A, Gorbunova V. Translation fidelity coevolves with longevity. Aging Cell, 2017.
- Nieborowska-Skorska M, …, Gorbunova V, …, Skorski T. Gene expression and mutation-guided synthetic lethality eradicates proliferating and quiescent leukemia cells. The Journal of Clinical Investigation, 2017.
- Yang C, …, Gorbunova V, …, Paschal BM. Ubiquitin modification by the E3 ligase/ADP-ribosyltransferase Dtx3L/Parp9. Molecular Cell, 2017.
- Tian X, Seluanov A, Gorbunova V. Beyond Making Ends Meet: DNA-PK, Metabolism, and Aging. Cell Metabolism, 2017.
- Valenzano DR, Aboobaker A, Seluanov A, Gorbunova V. Non-canonical aging model systems and why we need them. The EMBO Journal, 2017.
- Li J, …, Gorbunova V, …, Sinclair DA. A conserved NAD+ binding pocket that regulates protein-protein interactions during aging. Science, 2017.
- Bozek K, …, Azpurua J, Gorbunova V, Seluanov A, …, Philipp Khaitovich. Lipidome determinants of maximal lifespan in mammals. Scientific Reports, 2017.
- Moskalev A, …, Gorbunova V, …, Seluanov A, …, Zhavoronkov A. A review of the biomedical innovations for healthy longevity. Aging (Albany NY), 2017.
2016
- Ma S, …, Seluanov A, Gorbunova V, …, Gladyshev VN. Cell culture-based profiling across mammals reveals DNA repair and metabolism as determinants of species longevity. Elife, 2016.
- Hewitt G, Carroll B, Rezazadeh S, …, Seluanov A, Gorbunova V, …, Korolchuk VI. SQSTM1/p62 mediates crosstalk between autophagy and the UPS in DNA repair. Autophagy, 2016.
- Van Meter M, Simon M, Tombline G, May A, Morello TD, Hubbard BP, Bredbenner K, Park R, …, Gorbunova V, Seluanov A. JNK Phosphorylates SIRT6 to Stimulate DNA Double-Strand Break Repair in Response to Oxidative Stress by Recruiting PARP1 to DNA Breaks. Cell Reports, 2016.
- Dokukin M, Ablaeva J, Kalaparthi V, Seluanov A, Gorbunova V, Sokolov I. Pericellular Brush and Mechanics of Guinea Pig Fibroblast Cells Studied with AFM. Biophysical Journal, 2016.
- Gorbunova V, Rezazadeh S, Seluanov A. Dangerous Entrapment for NRF2. Cell, 2016.
- Gorbunova V, Seluanov A. DNA double strand break repair, aging and the chromatin connection. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, 2016.
- Patrick A, Seluanov M, Hwang C, Tam J, Khan T, Morgenstern A, Wiener L, Vazquez JM, Zafar H, Wen R, Muratkalyeva M, Doerig K, Zagorulya M, Cole L, Catalano S, …, Tian X, Ablaeva J, …, Seluanov A, Gorbunova V. Sensitivity of primary fibroblasts in culture to atmospheric oxygen does not correlate with species lifespan. Aging (Albany NY), 2016.
- Koschmann C, …, Gorbunova V, …, Castro MG. ATRX loss promotes tumor growth and impairs nonhomologous end joining DNA repair in glioma. Science Translational Medicine, 2016.
- Van Meter M, Gorbunova V, Seluanov A. Comparative biology of aging: insights from long-lived rodent species. Handbook of the Biology of Aging, 2016.
2015
- Brohus M, Gorbunova V, …, Conover CA. The insulin-like growth factor system in the long-lived naked mole-rat. PLoS One, 2015
- MacRae SL, …, Seluanov A, Gorbunova V, Zhang ZD, Vijg J. DNA repair in species with extreme lifespan differences. Aging (Albany NY), 2015.
- Ma S, …, Seluanov A, Gorbunova V, …, Gladyshev VN. Organization of the Mammalian Ionome According to Organ Origin, Lineage Specialization, and Longevity. Cell Reports, 2015.
- Fang X, …, Gorbunova V, …, Seluanov A, Azpurua J, …, Jun Wang. Corrigendum: Genome-wide adaptive complexes to underground stresses in blind mole rats Spalax. Nature Communications, 2015.
- MacRae SL, …, Seluanov A, Gorbunova V, Vijg J, Zhang ZD. Comparative analysis of genome maintenance genes in naked mole rat, mouse, and human. Aging Cell, 2015.
- Tian X, Azpurua J, Ke Z, …, Gorbunova V, Seluanov A. (2015). INK4 locus of the tumor-resistant rodent, the naked mole rat, expresses a functional p15/p16 hybrid isoform. Proceedings of the National Academy of Sciences, 2015.
- Xu Z, …, Van Meter M, Seluanov A, Gorbunova V, Mao Z. SIRT6 rescues the age related decline in base excision repair in a PARP1-dependent manner. Cell Cycle, 2015.
2014
- Keane M, …, Seluanov A, Gorbunova V, …, de Magalhães JP. The Naked Mole Rat Genome Resource: facilitating analyses of cancer and longevity-related adaptations. Bioinformatics, 2014.
- Gorbunova V, Boeke JD, Helfand SL, Sedivy JM. Sleeping dogs of the genome. Science, 2014.
- Van Meter M, Kashyap M, Rezazadeh S, Geneva AJ, Morello TD, Seluanov A, Gorbunova V. SIRT6 represses LINE1 retrotransposons by ribosylating KAP1 but this repression fails with stress and age. Nature Communications, 2014.
- Gorbunova V, Seluanov A, Zhang Z, Gladyshev VN, Vijg J. Comparative genetics of longevity and cancer: insights from long-lived rodents. Nature Reviews Genetics, 2014.
- Vaidya A, Mao Z, Tian X, Spencer B, Seluanov A, Gorbunova V. Knock-in reporter mice demonstrate that DNA repair by non-homologous end joining declines with age. PLoS Genetics, 2014.
- Hine CM, Li H, Xie L, Mao Z, Seluanov A, Gorbunova V. Regulation of Rad51 promoter. Cell Cycle, 2014.
- Fang X, …, Gorbunova V, …, Seluanov A, Azpurua J, …, Wang J. Genome-wide adaptive complexes to underground stresses in blind mole rats Spalax. Nature Communications, 2014.
- Cao Y, …, Tian X, Seluanov A, Gorbunova V, Mao Z. Utilization of Rad51C promoter for transcriptional targeting of cancer cells. Oncotarget, 2014.
- Van Meter M, Gorbunova V, Seluanov A. SIRT6: a promising target for cancer prevention and therapy. Anticancer Genes, 2014.
- Ke Z, Vaidya A, Ascher J, Seluanov A, Gorbunova V. Novel husbandry techniques support survival of naked mole rat (Heterocephalus glaber) pups. Journal of the American Association for Laboratory Animal Science, 2014.
2013
- Yao H, Sundar IK, Gorbunova V, Rahman I. P21-PARP-1 pathway is involved in cigarette smoke-induced lung DNA damage and cellular senescence. PLoS One, 2013.
- Azpurua J, Ke Z, Chen IX, Zhang Q, Ermolenko DN, Zhang ZD, Gorbunova V, Seluanov A. Naked mole-rat has increased translational fidelity compared with the mouse, as well as a unique 28S ribosomal RNA cleavage. Proceedings of the National Academy of Sciences, 2013.
- Yang JN, Seluanov A, Gorbunova V. Mitochondrial inverted repeats strongly correlate with lifespan: mtDNA inversions and aging. PLoS One, 2013.
- Tilgner K, …, Gorbunova V, …, Lako M. Brief report: a human induced pluripotent stem cell model of cernunnos deficiency reveals an important role for XLF in the survival of the primitive hematopoietic progenitors. Stem Cells, 2013.
- Tilgner K, …, Gorbunova V, …, Lako M. A human iPSC model of Ligase IV deficiency reveals an important role for NHEJ-mediated-DSB repair in the survival and genomic stability of induced pluripotent stem cells and emerging haematopoietic progenitors. Cell Death & Differentiation, 2013.
- Tian X, Azpurua J, Hine C, Vaidya A, Myakishev-Rempel M, Ablaeva J, Mao Z, Nevo E, Gorbunova V, Seluanov A. High-molecular-mass hyaluronan mediates the cancer resistance of the naked mole rat. Nature, 2013.
- Azpurua J, Yang JN, Van Meter M, Liu Z, Kim J, Lobo Ladd AA, Coppi AA, Gorbunova V, Seluanov A. IGF1R levels in the brain negatively correlate with longevity in 16 rodent species. Aging (Albany NY), 2013.
- Leu J, …, Gorbunova V, Lee Y. Enhanced cellular radiosensitivity induced by cofilin-1 over-expression is associated with reduced DNA repair capacity. International journal of radiation biology, 2013.
2012
- Van Meter M, Seluanov A, Gorbunova V. Forever young? Exploring the link between rapamycin, longevity and cancer. Cell Cycle, 2012.
- Gorbunova V, Hine C, Tian X, Ablaeva J, Gudkov AV, Nevo E, Seluanov A. Cancer resistance in the blind mole rat is mediated by concerted necrotic cell death mechanism. Proceedings of the National Academy of Sciences, 2012.
- Mao Z, Tian X, Van Meter M, Ke Z, Gorbunova V, Seluanov A. Sirtuin 6 (SIRT6) rescues the decline of homologous recombination repair during replicative senescence. Proceedings of the National Academy of Sciences, 2012.
- Mao Z, Ke Z, Gorbunova V, Seluanov A. Replicatively senescent cells are arrested in G1 and G2 phases. Aging (Albany NY), 2012.
- Anisimov VN, …, Gorbunova V, …, Seluanov A, …, Zimniak P. The second international conference “genetics of aging and longevity”. Aging (Albany NY), 2012.
- Rahman I, Kinnula VL, Gorbunova V, Yao H. SIRT1 as a therapeutic target in inflammaging of the pulmonary disease. Preventive medicine, 2012.
- Hine CM, Seluanov A, Gorbunova V. Rad51 promoter-targeted gene therapy is effective for in vivo visualization and treatment of cancer. Molecular Therapy, 2012.
2011
- Fong V, …, Hine C, Gorbunova V, Seluanov A, Dewhurst S. Adenoviral vector driven by a minimal Rad51 promoter is selective for p53-deficient tumor cells. PLoS One, 2011.
- Van Meter M, Mao Z, Gorbunova V, Seluanov A. SIRT6 overexpression induces massive apoptosis in cancer cells but not in normal cells. Cell Cycle, 2011.
- Van Meter M, Mao Z, Gorbunova V, Seluanov A. Repairing split ends: SIRT6, mono-ADP ribosylation and DNA repair. Aging (Albany NY), 2011.
- Mao Z, Hine C, Tian X, Van Meter M, Au M, Vaidya A, Seluanov A, Gorbunova V. SIRT6 promotes DNA repair under stress by activating PARP1. Science, 2011.
2010
- Seluanov A, Vaidya A, Gorbunova V. Establishing primary adult fibroblast cultures from rodents. JoVE (Journal of Visualized Experiments), 2010.
- Seluanov A, Mao Z, Gorbunova V. Analysis of DNA double-strand break (DSB) repair in mammalian cells. JoVE (Journal of Visualized Experiments), 2010.
- Gorbunova V, Seluanov A. A comparison of senescence in mouse and human cells. Cellular Senescence and Tumor Suppression, 2010.
2009
- Seluanov A, Hine C, Azpurua J, Feigenson M, Bozzella M, Mao Z, Catania KC, Gorbunova V. Hypersensitivity to contact inhibition provides a clue to cancer resistance of naked mole-rat. Proceedings of the National Academy of Sciences, 2009.
- Mao Z, Jiang Y, Liu X, Seluanov A, Gorbunova V. DNA repair by homologous recombination, but not by nonhomologous end joining, is elevated in breast cancer cells. Neoplasia, 2009.
- Gorbunova V, Seluanov A. Coevolution of telomerase activity and body mass in mammals: from mice to beavers. Mechanisms of ageing and development, 2009.
2008
- Hine CM, Seluanov A, Gorbunova V. Use of the Rad51 promoter for targeted anti-cancer therapy. Proceedings of the National Academy of Sciences, 2008.
- Seluanov A, Hine CM, Bozzella M, …, Gorbunova V. Distinct tumor suppressor mechanisms evolve in rodent species that differ in size and lifespan. Aging Cell, 2008.
- Mao Z, Bozzella M, Seluanov A, Gorbunova V. Comparison of nonhomologous end joining and homologous recombination in human cells. DNA Repair, 2008.
- Mao Z, Bozzella M, Seluanov A, Gorbunova V. DNA repair by nonhomologous end joining and homologous recombination during cell cycle in human cells. Cell Cycle, 2008.
- Gorbunova V, Bozzella MJ, Seluanov A. Rodents for comparative aging studies: from mice to beavers. Age, 2008.
- Dion V, …, Seluanov A, Gorbunova V, Wilson JH. Genome-wide demethylation promotes triplet repeat instability independently of homologous recombination. DNA Repair, 2008.
2007
- Seluanov A, Danek J, Hause N, Gorbunova V. Changes in the level and distribution of Ku proteins during cellular senescence. DNA Repair, 2007.
- Gorbunova V, Seluanov A, Mao Z, Hine CM. Changes in DNA repair during aging. Nucleic Acids Research, 2007.
- Mao Z, Seluanov A, Jiang Y, Gorbunova V. TRF2 is required for repair of nontelomeric DNA double-strand breaks by homologous recombination. Proceedings of the National Academy of Sciences, 2007.
- Seluanov A, Chen Z, Hine CM, …, Gorbunova V. Telomerase activity coevolves with body mass not lifespan. Aging Cell, 2007.
- Shi X, Seluanov A, Gorbunova V. Cell divisions are required for L1 retrotransposition. Molecular and cellular biology, 2007.
2005
- Gorbunova V, Seluanov A. Making ends meet in old age: DSB repair and aging. Mechanisms of ageing and development, 2005.
2004
- Gorbunova V, Seluanov A, Mittelman D, Wilson JH. Genome-wide demethylation destabilizes CTG.CAG trinucleotide repeats in mammalian cells. Human molecular genetics, 2004.
- Seluanov A, Mittelman D, Pereira-Smith OM, Wilson JH, Gorbunova V. DNA end joining becomes less efficient and more error-prone during cellular senescence. Proceedings of the National Academy of Sciences, 2004.