Headshot of Professor Jiang.

Yishu Jiang

she/her/hers

Assistant Professor of Biochemistry and Biophysics

PhD, Northwestern University

Office Location
448 Hutchison Hall
Web Address
Website

Office Hours: By appointment

Research Overview

In the Jiang group, we are interested in combining space and time-resolve spectroscopy to study, utilize and create excited-state species inside biological systems. Current mechanistic investigations and applications of these systems remain in vitro, and we are pursuing the possibility of in vivo measurements. Our lab therefore will employ an interdisciplinary approach based on organic synthesis, physical chemistry and biochemistry.

A graphic image depicting the kinetics, imaging, and catalysis of a chemical reaction.
Figure: The theme of Jiang lab featuring the mechanism study, imaging application, and photocatalysis optimization of proteins hosting excited-state chemistry in biological systems.

Research Interests

  • Biophysical chemistry
  • Catalysis
  • Ultrafast spectroscopy and cell imaging

Selected Publications

  • Xie, X. §; Jiang, Y. §; Chang, C. J., LOV thy neighbor: Mapping protein interactomes by genetically encodable photoproximity labeling. Proceedings of the National Academy of Sciences 2023, 120 (20), e2305211120.1.
  • Jiang, Y.; López-Arteaga, R.; Weiss. E.A.*, Quantum Dots Photocatalyze Intermolecular 1 Cycloadditions of Aromatic Alkenes Adsorbed to their Surfaces via van der Waals Interactions, Journal of the American Chemical Society2022, 144 (9), 3782–3786.
  • Jiang, Y.; Yang, M.; Wu, Y.; Lopez-Arteaga, R.; Rogers, C. R.; Weiss, E. A.*, Chemo- and Stereoselective Intermolecular [2+2] Photocycloaddition of Conjugated Dienes using Colloidal Nanocrystal Photocatalysts, Chem Catalysis 2021, 1 (1), 106-116.
  • Jiang, Y.; Weiss, E. A.*, Colloidal Quantum Dots as Photocatalysts for Triplet Excited State Reactions of Organic Molecules. Journal of the American Chemical Society 2020, 142 (36), 15219-15229.
  • Jiang, Y.; Wang, C.; Rogers, C. R.; Kodaimati, M. S.; Weiss, E. A.*, Regio-and diastereoselective intermolecular [2+ 2] cycloadditions photocatalysed by quantum dots. Nature chemistry 2019, 11 (11), 1034-1040.