James D Fry
Associate Professor
Chair of Undergraduate Advising
PhD
Research Active
- Office Location
- 318 Hutchison
- Telephone
- (585) 275-7835
Office Hours: By appointment
Research Overview
I am currently doing theoretical work on the evolution of mate choice and exaggerated sexually-selected traits (e.g., Fry 2022, 2024). I am no longer taking undergraduate researchers, graduate students, or postdocs.
Research Interests
- Genetics of ecological adaptation in Drosophila
- Evolutionary effects of deleterious mutations
- Quantitative-genetic theory and methodology
Selected Publications
- Fry, J. D. 2024. A reformulation of Fisher's runaway identifies the heritability of mate choices as a key parameter and highlights limitations of the hypothesis. Proceedings of the Royal Society B: 291: 20232366.
- Fry, J. D. 2022. A reexamination of theoretical arguments that indirect selection on mate preference is likely to be weaker than direct selection. Evolution Letters 6.
- Zhu, J., and J. D. Fry. 2018. Effects of a low dose of ethanol on mating success of Drosophila melanogaster males: implications for the evolution of ethanol resistance? Entomologia Experimentalis et Applicata 166:801–809.
- Chakraborty, M., and J. D. Fry. 2016. Evidence that environmental heterogeneity maintains a detoxifying enzyme polymorphism in Drosophila melanogaster. Current Biology 26:219-223.
- Chakraborty, M. and J. D. Fry. 2015. Parallel functional changes in independent testis-specific duplicates of Aldehyde dehydrogenase in Drosophila. Molecular Biology and Evolution 32: 1029–1038.
- Zhu, J., and J. D. Fry. 2015. Preference for ethanol in feeding and oviposition in temperate and tropical populations of Drosophila melanogaster. Entomologia Experimentalis et Applicata 155: 64–70.
- Fry, J.D. 2014. Mechanisms of naturally-evolved ethanol resistance in Drosophila melanogaster. Journal of Experimental Biology 217: 3996-4003.
- Yampolsky, L., G. Glazko and J. D. Fry. 2012. Evolution of gene expression and expression plasticity in long-term experimental populations of Drosophila melanogaster maintained under constant and variable ethanol stress. Molecular Ecology, 21: 4287–4299.
- Chakraborty, M., and J. D. Fry. 2011. Drosophila lacking a homologue of mammalian ALDH2 have multiple fitness defects. Chemico-Biological Interactions 191: 296-302.
- Fry, J.D. 2010. The genomic location of sexually antagonistic variation: some cautionary comments. Evolution64-5: 1510-1516.
- Fry, J.D. 2009. Laboratory experiments on speciation. Pages 631-656 in T. Garland and M. Rose, eds., Experimental Evolution: Methods and Applications. University of California Press, Berkeley.
- 2008. A world-wide polymorphism in Aldehyde dehydrogenase in Drosophila melanogaster: evidence for selection mediated by dietary ethanol. Evolution62:66-75.
- 2006. Aldehyde dehydrogenase is essential for both adult and larval ethanol resistance in Drosophila melanogaster. Genet. Res.87:87-92.
- 2005. Widespread correlations between dominance and homozygous effects of mutations: implications for theories of dominance.Genetics171:385-392.
- 2004. On the rate and linearity of viability declines in Drosophila mutation-accumulation experiments: genomic mutation rates and synergistic epistasis revisited.Genetics166:797-806.
- Fry, J. D. 2004. Estimation of genetic variances and covariances by Restricted Maximum Likelihood using PROC MIXED. Pages 11-34 in A. Saxton, ed., Genetic Analysis of Complex Traits with SAS. SAS Institute, Cary, NC. [programs]
- 2003. Detecting ecological trade-offs using selection experiments.Ecology84:1672-1678.
- 2003. Multilocus models of sympatric speciation: Bush vs. Rice vs. Felsenstein.Evolution57:1735-1746.
- 2001. Direct and correlated responses to selection for larval ethanol tolerance in Drosophila melanogaster.Evol. Biol.14:296-309.